What is the Crystal Form Consortium? 

In August 2008, the CCDC launched the Crystal Form Consortium. Bringing together development chemists from leading companies in industry, with software, database and research experts at the CCDC. Currently, the consortium has 12 member organisations spanning from major pharmaceutical companies around the world.

Together the members are working to leverage the vast wealth of structural knowledge in the CSD together with the expertise of solid state scientists, to provide structural informatics tools and approaches for the rational design of the solid form.


Our Goal: 

To provide structural informatics tools and approaches for the rational design of the solid form.


Our aims: 

We are developing software which can:

  • Guide decision making in the solid form selection  
  • Aid the engineering of new solid forms 
  • Rationalise the influence of bulk and surface upon materials properties
  • Provide novel insights and ultimately reduce risks in development phase

Why we are doing this:

We want to develop software that is easy and intuitive to use. We want the software we design to do more than just aid in investigation, we want to be able to achieve clear answers to our investigations.


Full Interaction Maps calculated for CSD Entry DEDMUX

Full Interaction Maps calculated for CSD Entry DEDMUX

Achievements:

The close collaboration of industry development scientists and CCDC experts has already guided the delivery of many tools including:

  • Hydrogen Bond Propensity (HBP)
  • H-Bond Coordination Quick View
  • Molecular Complementarity
  • Full Interaction Maps
  • Hydrate Analyser
  • Solvate Analyser
  • Aromatics Analyser

The software tools we have developed with the Crystal Form Consortium are available as part of the CSD-Materials suite.


If you want to know more about Crystal Form Consortium membership and how it could benefit your solid form development, email us with any questions.