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  • CSD in action: CSD-validated data helps discover compounds with 50% increase in potency for treatment of SMA

    Wed, 11 May 2022 13:54:00 GMT

    In this article we discuss research carried out by scientists at Novartis using the Cambridge Structural Database (CSD) in the development of potent small-molecule splicing modulators for the treatment of spinal muscular atrophy (SMA). This is part of our series highlighting examples of​​ the Cambridge Crystallographic Data Centre (CCDC) tools in action by scientists around the world.

    Continue reading…
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