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ConQuest fails with "ValueError: No JSON object could be decoded" on RHEL 8

Solution

On some versions of Linux including RHEL 8 and clones, ConQuest will fail to start with an error message

ValueError: No JSON object could be decoded

This is a known bug and the workaround is to rename or delete the file CCDC/ccdc-software/conquest/lib/libcrypto.so.1.1 so that ConQuest uses the system libraries instead.